Canadian Prime Minister Justin Trudeau has hit out at protests by truckers around the country as "unacceptable".
Speaking to parliament in Ottawa, he defended the federal Covid restrictions that have prompted truckers to converge on the nation's capital.
Ottawa police meanwhile warned protesters could be arrested, and a conviction might cost them their jobs.
The nationwide protests against pandemic restrictions have been going on for two weeks.
"Blockages, illegal demonstrations are unacceptable, and are negatively impacting businesses and manufacturers," Mr Trudeau said.
"We must do everything to bring them to an end."
He said the protesters are "trying to blockade our economy, our democracy and our fellow citizens' daily lives".
"It has to stop."
Mr Trudeau returned to Parliament this week following a week-long isolation after he caught coronavirus.
Since Monday drivers have been blocking the largest international suspension bridge in the world at a border crossing that makes up around a quarter of US-Canada trade.
The closure of the Ambassador Bridge by about 100 protesters in their big rigs has been denounced by trade groups.
About 400 trucks remain in downtown Ottawa after arriving there late last month. Police said on Wednesday that the protesters could be charged with "mischief to property" due to their blocking of local residents' "lawful use, enjoyment and operation of their property".
Ottawa police warned that "anyone blocking streets or assisting others in the blocking of streets may be committing a criminal offence".
They added that a criminal conviction could result in seizure of their vehicles, and an inability to enter the US. The police force also hiked penalties for noise, engine idling and other infractions in the city to C$1,000 ($790, £585) per offence.
The truckers are protesting against a rule requiring truckers entering Canada to be fully immunised against coronavirus. The demonstrators have also voiced opposition to Covid passports and mask mandates.
Mr Trudeau has refused to budge on federal Covid measures, even as provinces begin lifting their restrictions.
Alberta, Saskatchewan, Quebec and Prince Edward Island have all announced plans to lift most mitigation measures this month. Nova Scotia and New Brunswick have also announced plans to lift some restrictions.
On Tuesday, Alberta Premier Jason Kenney said pandemic-related restrictions had "disrupted and even destroyed livelihoods" in the province.
In Coutts, Alberta, on the border with the US state of Montana, RCMP officers warned they would take enforcement action on Wednesday to remove dozens of trucks that have been blocking that international crossing for about two weeks.
"Really it's going to be up to them," said RCMP Superintendent Roberta McKale, calling on them to move on their own.
"Up until this point it's been us asking them and this afternoon we don't have an option, we're going to have to use our enforcement options to have that happen."
Mr Trudeau has faced criticism from within his own party over his handling of the protests, which come as infections from the Omicron variant decline significantly.
Quebec MP Joël Lightbound, a fellow Liberal, criticised the prime minister this week for "demonising" groups that disagree with Covid mandates.
"It's becoming harder and harder to know when public health stops and where politics begins," Mr Lightbound said. "It's time to stop dividing Canadians and pitting one part of the population against another."
Interim Conservative leader Candice Bergen accused Mr Trudeau of wanting a "permanent pandemic".
"The prime minister needs to put his ego aside," she said. "He needs to do what's right for the country. He needs to end the mandates. He needs to end the restrictions."
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