A team in the Babraham Institute in Cambridge has successfully rejuvenated a 53-year-old woman's skin cells to look and behave like a 23-year-old's, the research center announced on Thursday.
The team had initially set out to create embryonic stem cells, which can divide into any type of cell in the body, using adult cells.
Nobel Award winner Shinya Yamanaka, a researcher at Kyoto University in Japan, first turned "normal" cells that have a specific function into stem cells back in 2006.
The BBC reported German molecular biologist Wolf Reik, postdoctoral student Diljeet Gill, and a team at Babraham Institute built upon Yamanaka's work.
Yamanaka grew stem cells by exposing adult cells to four molecules for about 50 days - a unique method he named iPS. Reik and Gill's team exposed skin cells to the same molecules for only 13 days, then let them grow under natural conditions.
By studying collagen production in the cells, the researchers found age-related changes on skin cells were removed and they temporarily lost their identity. After growing under normal conditions for a period of time, researchers found the cells began behaving like skin cells again.
The team then measured age-related biological changes in the reprogrammed cells, and found the cells matched the profile of those 30 years younger to reference data sets, Gill said in a release.
"I remember the day I got the results back and I didn't quite believe that some of the cells were 30 years younger than they were supposed to be," Gill told BBC. "It was a very exciting day."
The research was done in a lab, and Reik told the BBC the team cannot take the technique to a clinic because the technique used to rejuvenate the cells has the potential to increase the risk of cancer, likely due to creating lasting genetic changes within cells.
But the biologist said the method of rejuvenating cells could help speed up healing time in burn victims, and may eventually extend human life.
"Eventually, we may be able to identify genes that rejuvenate without reprogramming, and specifically target those to reduce the effects of aging," Reik said in a press release.
The researchers published their findings in the journal eLife on April 8.
Latest Stories
-
Osu Castle hosts diplomatic showcase of wellness as Ghana, India unites for International Day of Yoga
33 minutes -
U.S. and Israeli Strikes on Iran: A Racist, Colonialist Assault on Sovereignty
57 minutes -
Your unfair insinuations make me doubt your intentions even more – Prof Gyampo refutes OSP’s account of SML raid contact
1 hour -
Prof Gyampo called and texted OSP during raid on SML – OSP claims
2 hours -
Nigeria sprinter Favour Ofili switches allegiance to Turkey
2 hours -
Ahwoi and Bartels-Kodwo families open residence to mourners following passing of Ama Adoma Bartels-Kodwo
2 hours -
Mpox Outbreak: Western Regional Health Directorate springs into action
2 hours -
OSP rebuts Gyampo’s ‘vendetta’ allegation over investigation into Ofori-Atta
3 hours -
Ukraine still holds ground inside Russia’s Kursk, commander says
4 hours -
Nkwanta South MCE pays courtesy call on national Chief Imam, seeks prayers for peace
4 hours -
Kwasi Sibo helps power Real Oviedo to LaLiga promotion after 24-year wait
4 hours -
Broadcast and Build: How 2 of Ghana’s leading media giants are driving a bold socio-economic reset through strategic trade fairs
4 hours -
Actress Kalsoume Sinare named Ghana’s ambassador to Spain
5 hours -
Nkyinkyim says band music pays, but only with proper investment
6 hours -
Ecobank-JoyNews Habitat Fair: Day 3 promises mouth-watering discounts and great sales
6 hours