Serie A leaders Napoli are out of the Coppa Italia after a last-16 penalty shootout defeat by Cremonese.
The visitors, bottom of Italy's top flight, took the lead through Charles Pickel.
First-half goals from Juan Jesus and Giovanni Simeone turned the game on its head, but Felix Afena-Gyan levelled late on.
Cremonese's Leonardo Sernicola was sent off in extra time, but the visitors prevailed 5-4 in the shootout.
Stanislav Lobotka missed Napoli's fourth spot-kick, while Cremonese scored all five of theirs to stun the 2019-20 winners.
Luciano Spalletti's side are nine points clear at the top of Serie A, having thumped third-placed Juventus 5-1 on Friday.
Cremonese are without a win in Serie A this season, leaving them stranded at the foot of the table and nine points adrift of safety.
Latest Stories
-
CLOGSAG vows to resist partisan appointments in Civil, Local Government Service
31 minutes -
Peasant Farmers Association welcomes Mahama’s move to rename Agric Ministry
32 minutes -
NDC grateful to chiefs, people of Bono Region -Asiedu Nketia
34 minutes -
Ban on smoking in public: FDA engages food service establishments on compliance
35 minutes -
Mahama’s administration to consider opening Ghana’s Mission in Budapest
37 minutes -
GEPA commits to building robust systems that empower MSMEs
40 minutes -
Twifo Atti-Morkwa poultry farmers in distress due to high cost of feed
42 minutes -
Central Region PURC assures residents of constant water, power supply during yuletide
43 minutes -
Election victory not licence to misbehave – Police to youth
45 minutes -
GPL 2024/2025: Nations thrash struggling Legon Cities
47 minutes -
Electoral offences have no expiry date, accountability is inevitable – Fifi Kwetey
48 minutes -
Ghanaians to enjoy reliable electricity this Christmas – ECG promises
55 minutes -
Police deny reports of election-related violence in Nsawam Adoagyiri
58 minutes -
‘We’re not brothers; we’ll show you where power lies’ – Dafeamekpor to Afenyo-Markin
1 hour -
EPA says lead-based paints are dangerous to health, calls for safer alternatives
3 hours