Labour Party is on course for a landslide victory as the Conservatives face their worst-ever general election night, early results suggest.
Sir Keir Starmer is heading to Downing Street with a majority of 170, according to an exit poll for the BBC, ITV and Sky, with the Tories reduced to 131 MPs.
In his constituency victory speech, the Labour leader said it was "time for us to deliver".
Reform UK is taking large amounts of votes from the Tories and has finished second in a string of seats, as well as getting its first MP elected, with leader Nigel Farage's result still to come.
The Liberal Democrats are also set to benefit from a collapse in Tory support and are predicted to get 61 MPs - their best result since 2010.
The Scottish National Party is facing the prospect of losing 38 seats as Labour returns to dominance in Scotland.
The Green Party of England and Wales is predicted to double its number of MPs to two and Plaid Cymru is set to get four MPs. Others are forecast to get 19 seats.
Sir Keir's predicted landslide would be just short of the 179 majority won by Tony Blair in 1997 and the party may achieve it on a smaller share of the vote than former leader Jeremy Corbyn won in 2017, according to Sir John Curtice.
It will mean a Labour prime minister in Downing Street for the first time since 2010 and a battle for the future direction of the Conservatives if, as seems likely, Rishi Sunak stands down as leader.
Labour's Rachel Reeves - who looks set to be the first female chancellor in a few hours' time - said she did not want to pre-empt the result but it was "clear that the British people have voted for change" and a "brighter future" under Sir Keir Starmer.
In her victory speech in Leeds West and Pudsey, she said: "We will not let you down and I can't wait to get started."
The Conservatives may avoid the wipe-out predicted by some opinion polls but they are still set for the worst result in the party's history, losing 241 MPs - a devastating blow after 14 years in government.
Defence Secretary Grant Shapps and Justice Secretary Alex Chalk have become the first cabinet ministers to lose their seats, with other senior Tory figures such as Penny Mordaunt and Jeremy Hunt looking vulnerable.
Former attorney general Sir Robert Buckland, the first Tory MP to lose his seat as results began rolling in, told the BBC his party was facing "electoral Armageddon" and Labour's likely victory was a "big vote for change".
And he angrily lashed out at colleagues, such as former home secretary Suella Braverman, for what he called "spectacularly unprofessional and ill-disciplined" behaviour during the campaign.
"I'm fed up of personal agendas and jockeying for position," he added, warning that the upcoming Tory leadership contest was "going to be like a group of bald men arguing over a comb".
Lee Anderson, who defected to Reform from the Tories, became the party's first elected MP in his Ashfield constituency, beating the Labour candidate into second place.
The exit poll predicts Reform will get around 13 MPs - more than previously expected.
The Liberal Democrats are, meanwhile, set to squeeze the Tory vote in the south of England, with leader Sir Ed Davey saying: "It looks like this will be our best result for a generation."
Former cabinet minister Sir Jacob Rees-Mogg, who is also under threat from the Lib Dems, said it was "clearly a terrible night" for the Conservatives.
He said voters had been put off by the revolving door in No 10 which saw Boris Johnson replaced first by Liz Truss and then by Mr Sunak.
Scotland's Deputy First Minister Kate Forbes said the SNP are facing a "very difficult night", as the exit poll predicts they will lose 38 seats.
She added: “Of course we take on board what the people of Scotland, the voters, are saying in this election and we will set out our agenda to regain and rebuild the trust of voters across Scotland.”
Rishi Sunak had insisted he could still win right to the end despite failing to make a dent in Labour's commanding opinion poll lead over the six-week campaign.
Mr Sunak surprised many in his own party by announcing a summer election.
But his campaign was hit by a series of gaffes, from the rain-drenched announcement in Downing Street to his decision to leave a D-Day celebration in Normandy early to record a TV interview and confused messaging about a Labour "super majority".
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