Mario Mandzukic, Paulo Dybala and Gonzalo Higuain scored as defending champions Juventus downed Cagliari 3-0 on Saturday in their Serie A opener.
Juventus sealed a record sixth straight title last season but lost the Champions League final 4-1 to Real Madrid.
Saturday's win was also Juve's first in their newly-named Allianz Stadium, following a recent sponsorship agreement.
Napoli are away to Verona in Saturday's late game while Roma, Inter Milan and AC Milan are all in action on Sunday.
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