Ghana will go 4-3-3 against Mali later on Tuesday when they clash in a friendly international in Paris.
The game in France comes after the Stars lost 2-1 to Senegal on Saturday.
In his quest to make Ghana look pliable, Grant will try a more wing-based approach after going with a traditional 4-4-2 in Le Havre.
“It’s a different target now to when in a tournament,” Grant said.
“In friendly matches, you have a chance to try different situations and different systems...we will start with the 4-3-3 and see how it goes.”
In Equatorial Guinea, the Stars mixed a fast-paced style centred on wingplay with the more traditional role.
Ghana’s squad:
Goalkeepers: Razak Braimah (Mirandes, Spain), Fatau Dauda (AshGold)
Defenders: Harrison Afful (Esperance, Tunisia), John Boye (Erciyesspor, Turkey), Jonathan Mensah (Evian, France), Jeffery Schlupp (Leicester City, England), Gyimah Edwin (Mpumalanga Black Aces, South Africa), Daniel Amartey, (FC Copenhagen, Denmark)
Midfielders: Rabiu Mohammed (Krasnodar, Russia), Emmanuel Agyemang-Badu (Udinese, Italy), Afriyie Acquah (Sampdoria, Italy), Solomon Asante (T.P. Mazembe, DR Congo), Christian Atsu (Everton, England), Mubarak Wakaso (Celtic, Scotland), Andre Ayew (Olympique Marseille, France), Frank Acheampong (Anderlecht, Belgium), Seidu Salifu (Club Africaine, Tunisia)
Forwards: Jordan Ayew (Lorient, France), Kwesi Appiah (Crystal Palace, England), Ebenezer Assifuah (FC Sion, Switzerland), Richmond Boakye-Yiadom (Atalanta, Italy), David Accam (Chicago Fire, U.S.A)
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