A North London derby is a must-win encounter for either side, be it in the cup or league, but Mauricio Pochettino and Arsene Wenger each have their own reasons to target victory.
The mood of both sides is dramatically different to where it was prior to the international break, with the hosts riding a wave of confidence after Heung-min Son’s three goals in two games suggested there may be life beyond Harry Kane.
A win against their bitter rivals will raise hopes that Spurs’ slow start to the season is well and truly over.Will Arsenal triumph away from home or can Tottenham continue their good run?
Liverpool welcome League Two side Carlisle to Anfield in the Capital One Cup hoping for a win to keep the pressure off manager Brendan Rodgers.
The Reds boss has come under scrutiny after an indifferent start in the Premier League has followed another big overhaul of his playing staff in the summer.
After winning the their first two games of the season, Liverpool have not won in five matches. In comparison, Carlisle have made a decent start to their campaign. They currently lie in 10th but are level on points with Oxford United,who are in fifth.
The Cumbrians also possess England's leading scorer in Jabo Ibehre, who has netted 10 times in 11 appearances since joining Carlisle on a free transfer in the summer.
Chelsea striker Diego Costa begins a three-match suspension after being found guilty of violent conduct.
The Spain international was banned after clashing with Laurent Koscielny during the Blues' 2-0 Premier League win over Arsenal at Stamford Bridge.
Captain John Terry and striker Radamel Falcao will start the game but goalkeeper Thibaut Courtois (knee) and midfielder Willian are sidelined.
Isaiah Osbourne is a doubt for League One Walsall because of a knee injury.
Manchester United go in search of their first trophy in three seasons but will face a tough test as they welcome Ipswich to Old Trafford in the third round of the Capital One Cup on Wednesday.
Following last season's embarrassing 4-0 defeat to MK Dons, the Red Devils will be looking to vastly improve and carry on their fine domestic form.
United currently lie in second place in the Premier League and have lost only one game in the league so far.
Ipswich will be no pushovers, however, and Mick McCarthy's side are in good form themselves. They are fourth in the Championship and breezed past Doncaster 4-1 in the previous round.
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