Romelu Lukaku's representatives say the Inter Milan striker was racially abused by Juventus fans after scoring a late penalty before being sent off in the Coppa Italia draw in Turin.
Lukaku was shown a second yellow card for celebrating in front of the home fans after his 95th-minute spot-kick.
Michael Yormark, president of Roc Nation Sports International, said the abuse was "beyond despicable".
Scuffles broke out between players from both sides after the equaliser.
Inter captain Samir Handanovic and midfielder Juan Cuadrado were shown red cards after the final whistle, with the fracas continuing down the tunnel.
"Tonight's racist remarks made towards Romelu Lukaku by Juventus fans in Turin were beyond despicable and cannot be accepted," said Yormark in a statement.
"Romelu scored a penalty late in the game. Before, during and after the penalty, he was subjected to hostile and disgusting racist abuse.
"Romelu celebrated in the same manner he has previously celebrated goals. The referee's response was to award a yellow card to Romelu.
"Romelu deserves an apology from Juventus and I expect the league to condemn the behaviour of this group of Juventus supporters immediately.
"The Italian authorities must use this opportunity to tackle racism, rather than punish the victim of the abuse."
Lukaku, who returned to Inter on loan from Chelsea last summer, suffered racist abuse during his first spell at Inter between 2019 and 2021.
In September 2019 he said the game "was going backwards" after he was racially abused by Cagliari fans.
Cagliari were later cleared of racist chanting, with Piara Powar - chief of anti-discriminatory body Fare - claiming the disciplinary systems to combat racism in Italian football were "not fit for purpose".
In September 2021, Lukaku said racism in football was at an "all-time high" and that players, football authorities and social media could do more to tackle the issue.
In January, Serie A opened an investigation into allegations of racist abuse aimed towards Lukaku by Napoli fans.
The same day Lazio supporters racially abused Samuel Umtiti and Lameck Banda of Lecce, with the club later ordered to close part of their stadium for their next match.
In the Coppa Italia tie, midfielder Cuadrado put Juventus ahead in the 83rd minute before Gleison Bremer's handball presented Inter with the added-time spot-kick that Lukaku converted.
Cremonese host Fiorentina in the second semi-final on Wednesday, with the second legs of both ties set to be played on 26 and 27 April.
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