Manchester United are expected to be without Marcus Rashford and Edinson Cavani for Thursday's Europa League last-16 first-leg tie against AC Milan.
Rashford was substituted during the 2-0 win against Manchester City on Sunday after injuring an ankle.
Fellow forward Cavani, meanwhile, missed the derby having only recently returned from a muscle injury.
Goalkeeper Dean Henderson will play again, with David de Gea absent after the birth of his first child.
Milan striker Zlatan Ibrahimovic will not face his former club because of a thigh injury, and the veteran Swede is one of a number of absentees.
The Italian side have also travelled without without Theo Hernandez, Ismael Bennacer, Hakan Calhanoglu, Ante Rebic and Mario Mandzukic.
Diogo Dalot, who is on loan from United, is able to play against his parent club.
'We want to go as far as we can'
With United 11 points behind Premier League leaders Manchester City, their best chances of winning silverware this season look to be in the Europa League and FA Cup.
"When you play for this club you are expected to win trophies and not just matches," said captain Harry Maguire.
"We're in three competitions and we want to go as far as we can in them all."
Latest Stories
-
Central Region schools and CIUCC celebrate United Nations Chinese Language Day
11 hours -
Maiden AshantiFest peaks this Easter weekend, Kumasi residents ready to participate in fun-filled activities
12 hours -
Joseph Nelson tackles potholes on Asem-asa N1 highway on Takoradi-Accra road
12 hours -
W/Regional Minister slams police officers allegedly accepting bribes from illegal miners
12 hours -
UEW expels postgraduate student over massive admission and certificate fraud scheme
12 hours -
GNPC’s EXPLORCO to drill first Voltaian Basin Well in 2026 as Ghana courts energy investors
12 hours -
“We have been caged” – GAFORB urges BoG to reassess forex operational guidelines
13 hours -
The idea is to give everyone a chance in football – CAF rep on African Schools Football Championship
13 hours -
MP Jerry Ahmed Shaib sounds alarm over prolonged ‘dumsor’ in Weija‑Gbawe, demands urgent action
13 hours -
Women and Girls Bleed Too: Shining the Light on haemophilia and bleeding disorders in Women and girls
14 hours -
‘Our galamsey fight is nothing but staged drama until the kingpins are dealt with’ – Prof Boadi
14 hours -
Ramadan Cup: Kudus, Kamaldeen donate trophy, medals and cash prize for 10th edition
14 hours -
Gov’t must act to end banditry and domestic terrorism in Bawku – Mamprugu overlord
14 hours -
A/R Minister announces plans to relocate Kumasi Central Prisons to help decongest the city
14 hours -
Your jobs are safe – Lands Minister assures Damang Mines workers
16 hours